| Nintendo Game Boy Color cart. |  Robot Wars - Metal Mayhem Model CGB-BRWP-UKV | 2000 | BBC Worldwide, Ltd. |
| Nintendo Game Boy Color cart. | Rocket Power - Gettin' Air Model CGB-BRUE-USA | 2001 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo Game Boy Color cart. |  Rocket Power - La Glisse de l'Extreme | 2001 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo Game Boy Color cart. | Rockman X - Cyber Mission Model DMG-BRXJ-JPN | 2000 | Capcom Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Rockman X2 - Soul Eraser Model CGB-BXRJ-JPN | 2001 | Capcom Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Rockman X3 | 200? | Guangzhou Li Cheng China |
| Nintendo Game Boy Color cart. | Rocky Mountain Trophy Hunter Model CGB-BRME-USA | 2000 | Infogrames Ent., Inc. CA, USA 20295 |
| Nintendo Game Boy Color cart. | Rocman X | 199? | Sachen Thin Chen co. Taiwan |
| Nintendo Game Boy Color cart. | Rokumon Tengai Mon-Colle-Knight GB Model CGB-BKDJ-JPN | 2000 | Kadokawa Shoten Japan |
| Nintendo Game Boy Color cart. | Roland Garros French Open Model CGB-BRGP-EUR | 2000 | Cryo Interactive Ent. |
| Nintendo Game Boy Color cart. | Ronaldo V-Football Model DMG-AORP-EUR | 1999 | Infogrames Europe 546430 |
| Nintendo Game Boy Color cart. | Ronaldo V-Football Model DMG-AORP-FAH | 1999 | Infogrames Interactive, Inc. 329720 |
| Nintendo Game Boy Color cart. | Ronaldo V-Soccer Model DMG-AORE-USA | 1999 | Infogrames Ent., Inc. CA, USA 20295 |
| Nintendo Game Boy Color cart. | Roswell Conspiracies - Aliens, Myths & Legends Model CGB-BCPE-USA | 2001 | Red Storm Ent. |
| Nintendo Game Boy Color cart. | Roswell Conspiracies - Aliens, Myths & Legends Model CGB-BCPP-EUR | 2001 | UBI Soft Creteil, France 307211 |
| Nintendo Game Boy Color cart. | Rox - 6=Six Model DMG-ARXE-USA | 2001 | Titus Gagny, France |
| Nintendo Game Boy Color cart. | Rox - 6=Six Model DMG-ARXJ-JPN | 1999 | Altron Corp. |
| Nintendo Game Boy Color cart. | Rox - 6=Six Model DMG-ARXP-EUR | 2001 | Titus Gagny, France |
| Nintendo Game Boy Color cart. | RPG Tsukuru GB Model CGB-A2QJ-JPN | 2000 | ASCII Corp. Japan |
| Nintendo Game Boy Color cart. | Rugrats - Time Travelers Model DMG-AVME-USA | 1999 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo Game Boy Color cart. | Rugrats - Time Travelers Model DMG-AVMP-EUR | 1999 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo Game Boy Color cart. | Rugrats - Totally Angelica Model CGB-BAGE-USA | 2000 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo Game Boy Color cart. | Rugrats - Totally Angelica Model CGB-BAGP-EUR | 2000 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo Game Boy Color cart. | Rugrats - Typisch Angelica Model CGB-BAGD-NOE | 2000 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo Game Boy Color cart. | Rugrats in Paris - The Movie Model CGB-BRPE-USA | 2000 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo Game Boy Color cart. | Rugrats in Paris - The Movie Model CGB-BRPP-EUR | 2000 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo Game Boy Color cart. | Rugrats in Paris - The Movie Model CGB-BRPX-ESP | 2001 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo Game Boy Color cart. | Sabrina - The Animated Series - Spooked! Model CGB-B4PE-USA | 2001 | Simon & Schuster Interactive |
| Nintendo Game Boy Color cart. | Sabrina - The Animated Series - Spooked! Model CGB-B4PP-UKV | 2001 | Simon & Schuster Interactive |
| Nintendo Game Boy Color cart. | Sabrina - The Animated Series - Zapped! Model CGB-BSGE-USA | 2000 | Simon & Schuster Interactive |
| Nintendo Game Boy Color cart. | Sabrina - The Animated Series - Zapped! Model CGB-BSGP-EUR | 2000 | Simon & Schuster Interactive |
| Nintendo Game Boy Color cart. | Sabrina - The Animated Series - Zapped! Model CGB-BSGX-EUU | 2000 | Simon & Schuster Interactive |
| Nintendo Game Boy Color cart. | Sakata Gorou Kudan no Renju Kyoushitsu Model DMG-AREJ-JPN | 1999 | Culture Brain |
| Nintendo Game Boy Color cart. | Sakura Taisen GB - Geki Hana Kumi Nyuutai! Model CGB-BRJJ-JPN | 2000 | Media Factory Japan |
| Nintendo Game Boy Color cart. | Sakura Taisen GB2 - Thunderbolt Sakusen Model CGB-BQYJ-JPN | 2001 | SEGA Corp. |
| Nintendo Game Boy Color cart. | Samurai Kid Model CGB-BS5J-JPN | 2001 | KOEI Co., Ltd. Japan |
| Nintendo Game Boy Color cart. |  San Francisco Rush - Extreme Racing | 199? | Midway Home Ent. |
| Nintendo Game Boy Color cart. | San Francisco Rush 2049 Model CGB-ASXE-USA | 2000 | Midway Home Ent. |
| Nintendo Game Boy Color cart. | San Francisco Rush 2049 Model CGB-ASXP-EUR | 2000 | Midway Home Ent. |
| Nintendo Game Boy Color cart. | San Guo Zhi - Ao Shi Tian Jia | 200? | Unknown China |
