| NEC PC-9801 Series 5.25in. disk |  Caramel Quest - Meitenkyuu no Megamizou | 1991 | Agumix Japan |
| NEC PC-9801 Series 5.25in. disk | Carax 92 | 1992 | Bio 100% Japan |
| NEC PC-9801 Series 5.25in. disk | Card Buster | 1993 | F-88 Japan |
| NEC PC-9801 Series 5.25in. disk | Card Buster 2 - Fukkatsu no Seihishaku | 1994 | F-88 Japan |
| NEC PC-9801 Series 5.25in. disk | Card Force 18 | 199? | Season Express Japan |
| NEC PC-9801 Series 5.25in. disk | Carmen Sandiego in Japan - Hannin Sagashite Nihon Zenkoku | 1989 | Broderbund Japan |
| NEC PC-9801 Series 5.25in. disk | Carmine | 1986 | Micro Cabin Co. Japan |
| NEC PC-9801 Series 5.25in. disk | Caroll | 1990 | System House Oh! Japan |
| NEC PC-9801 Series 5.25in. disk | Carrot Hunting | 199? | Unknown Japan |
| NEC PC-9801 Series 5.25in. disk | Casablanca ni Ai o - Satsujin-sha wa Jikuu o Koete Model NFTQ14004 | 1986 | Thinking Rabbit Japan |
| NEC PC-9801 Series 5.25in. disk | Case of Dungeons | 199? | Studio K2 Japan |
| NEC PC-9801 Series 5.25in. disk | Casino Dream | 199? | Unknown Japan |
| NEC PC-9801 Series 5.25in. disk | Casinopolis - Exceed Jack | 1995 | Misty Japan |
| NEC PC-9801 Series 5.25in. disk | Castle Excellent Model 2018107 | 1985 | ASCII Corp. Japan |
| NEC PC-9801 Series 5.25in. disk | Castle of Dr. Brain P | 1992 | Sierra On-Line, Inc. USA 20626 |
| NEC PC-9801 Series 5.25in. disk | Castles Model R-5180~81 | 1992 | Cross Media Soft Japan |
| NEC PC-9801 Series 5.25in. disk | Cat's Part-1 18 | 1993 | Cat's Pro Japan |
| NEC PC-9801 Series 5.25in. disk | Cattle Mutilation | 1993 | Onion Soft |
| NEC PC-9801 Series 5.25in. disk | Celery | 1989 | Software House Parsley Japan |
| NEC PC-9801 Series 5.25in. disk | Centurion - Defender of Rome | 1993 | Electronic Arts Victor, Inc. Japan |
| NEC PC-9801 Series 5.25in. disk | Cest la vie 18 | 1995 | May-Be Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | CG Story - Fuumashi Erika | 1991 | Explorer Japan |
| NEC PC-9801 Series 5.25in. disk | Chakra - Challenger Club | 1993 | Discovery Corp. Japan |
| NEC PC-9801 Series 5.25in. disk | Challenge the Touch-Type 2 | 199? | ASCII Corp. Japan |
| NEC PC-9801 Series 5.25in. disk | Chanko Nabe | 199? | WestSide Softhouse Japan |
| NEC PC-9801 Series 5.25in. disk | Chaos Angels | 1989 | ASCII Corp. Japan |
| NEC PC-9801 Series 5.25in. disk | Charade | 1995 | Apple Pie Japan |
| NEC PC-9801 Series 5.25in. disk | Charade Magic | 1992 | Heart Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Charm | 1992 | Acid Plan Japan |
| NEC PC-9801 Series 5.25in. disk | Charm 2 - Nijiiro no Kaze | 1994 | Acid Plan Japan |
| NEC PC-9801 Series 5.25in. disk | Check Six | 1993 | Pegasus Japan |
| NEC PC-9801 Series 5.25in. disk | Check Six 2 - Hekikuu no Ookami | 1994 | Pegasus Japan |
| NEC PC-9801 Series 5.25in. disk | Check Six 2 - Scenario Shuu Vol. 1 | 1994 | Pegasus Japan |
| NEC PC-9801 Series 5.25in. disk | Check Six 2 Special | 1994 | Pegasus Japan |
| NEC PC-9801 Series 5.25in. disk | Cherry Bomb - Chou Ojousama Sayaka-chan Nanpa Daisakusen | 1994 | Peppermint Kids Japan |
| NEC PC-9801 Series 5.25in. disk | Cherry Jam - Kanojo ga Hadaka ni Kigaetara | 1996 | JAM Japan |
| NEC PC-9801 Series 5.25in. disk | Cherry Moderate | 1996 | Ucom Japan |
| NEC PC-9801 Series 5.25in. disk | Chicks' Tale | 1995 | Riruhi's Party Japan |
| NEC PC-9801 Series 5.25in. disk | Chiemi | 1993 | Fairytale Japan |
| NEC PC-9801 Series 5.25in. disk | Chikashitsu no Ikenie | 199? | Unknown Japan |
