| Nintendo Switch cart. |  Shantae - Half-Genie Hero - Ultimate Edition | 2018 | XSEED Games |
| Nintendo Switch cart. |  Shantae - Half-Genie Hero - Ultimate Edition Model LA-H-AMSGA-EUR | 2018 | PQube, Ltd. |
| Nintendo Switch cart. | Shantae - Half-Genie Hero - Ultimate Edition Model LA-H-AMSGB-JPN | 2018 | Oizumi Amuzio Japan |
| Nintendo Switch cart. | Shantae and the Pirate's Curse | 2018 | Limited Run Games |
| Nintendo Switch cart. | Shelter Generations | 2018 | Super Rare Games |
| Nintendo Switch cart. | Shiin Model LA-H-AN62A-JPN | 2018 | Experience, Inc. Japan |
| Nintendo Switch cart. | Shikhondo - Soul Eater Model EAS-SW003 | 2018 | EastAsiaSoft |
| Nintendo Switch cart. | Shin Sangoku Musou 7 Empires Model LA-H-AGVYA-JPN | 2017 | KOEI Tecmo Games Co., Ltd. Japan |
| Nintendo Switch cart. | Shin Sangoku Musou 7 with Moushouden DX | 2018 | KOEI Tecmo Games Co., Ltd. Japan |
| Nintendo Switch cart. | Shingeki no Kyojin 2 - Final Battle | 2019 | KOEI Tecmo Games Co., Ltd. Japan |
| Nintendo Switch cart. | Shingeki no Kyojin 2 Model LA-H-AECNA-JPN | 2018 | KOEI Tecmo Games Co., Ltd. Japan |
| Nintendo Switch cart. | Shining Resonance Re:frain Model LA-H-AM7TA-JPN | 2018 | SEGA Corp. |
| Nintendo Switch cart. | Sid Meier's Civilization VI | 2018 | 2K Games, Inc. New York, NY, USA |
| Nintendo Switch cart. | Sine Mora EX | 2017 | T-HQ Nordic |
| Nintendo Switch cart. | Slain - Back from Hell | 2018 | Merge Games |
| Nintendo Switch cart. | Slime-san - Superslime Edition | 2018 | Limited Run Games |
| Nintendo Switch cart. | Snipperclips Plus - Cut It Out, Together! Model LA-H-AEXYA-UKV | 2017 | Nintendo Co., Ltd. Japan |
| Nintendo Switch cart. | Snipperclips Plus - Cut It Out, Together! Model LA-H-AEXYA-USA | 2017 | Nintendo of America, Inc. USA 45496 |
| Nintendo Switch cart. | SNK Heroines - Tag Team Frenzy Model LA-H-APVSA-JPN | 2018 | SNK Corp. Shin Nihon Kikaku Japan |
| Nintendo Switch cart. | Sonic Forces Model LA-H-ABQLC-EUR | 2017 | SEGA Corp. |
| Nintendo Switch cart. | Sonic Forces Model LA-H-ABQLC-JPN | 2017 | SEGA Corp. |
| Nintendo Switch cart. | Sonic Forces Model LA-H-ABQLC-KOR | 2017 | SEGA Corp. |
| Nintendo Switch cart. | Sonic Forces Model LA-H-ABQLC-USA | 2017 | SEGA Corp. |
| Nintendo Switch cart. | Sonic Mania | 2017 | SEGA Corp. |
| Nintendo Switch cart. | Sonic Mania Plus | 2018 | SEGA Corp. |
| Nintendo Switch cart. | Sonic Superstars | 2023 | SEGA of America, Inc. San Francisco, CA, USA |
| Nintendo Switch cart. | Sonic Superstars Model HAC-A7YPA-JPN | 2023 | SEGA Corp. |
| Nintendo Switch cart. | Sparklite | 2019 | Merge Games |
| Nintendo Switch cart. | Splatoon 2 Model LA-H-AAB6A-JPN | 2017 | Nintendo Co., Ltd. Japan |
| Nintendo Switch cart. | Splatoon 2 Model LA-H-AAB6B-AUS | 2017 | Nintendo Co., Ltd. Japan |
| Nintendo Switch cart. | Splatoon 2 Model LA-H-AAB6B-USA | 2017 | Nintendo of America, Inc. USA 45496 |
| Nintendo Switch cart. | Splatoon 2 Model LA-H-AAB6C-UKV | 2017 | Nintendo Co., Ltd. Japan |
| Nintendo Switch cart. | Sports Party Model LA-H-AFVXA-USA | 2018 | Ubisoft, Inc. San Francisco, CA, USA 08888 |
| Nintendo Switch cart. | Starlink - Battle for Atlas Model LA-H-AD8HA-UKV | 2018 | Ubisoft Ent. Montreuil sous Bois, France |
| Nintendo Switch cart. | Starlink - Battle for Atlas Model LA-H-AD8HA-USA | 2018 | Ubisoft, Inc. San Francisco, CA, USA 08888 |
| Nintendo Switch cart. | SteamWorld Dig 2 Model LA-H-ACATC-UKV | 2018 | Rising Star Games, Ltd. UK |
| Nintendo Switch cart. | Steins;Gate - Divergencies Assort | 2019 | 5pb. Japan |
| Nintendo Switch cart. | Steins;Gate Elite Model LA-H-AMNPA-JPN | 2018 | 5pb. Japan |
| Nintendo Switch cart. | Steredenn - Binary Stars | 2018 | Super Rare Games |
| Nintendo Switch cart. | Street Fighter - 30th Anniversary Collection | 2018 | Capcom Co., Ltd. Japan |
