| NEC PC-Engine HuCARD |  Son Son II Model H54G1003 | 1989 | NEC Avenue, Ltd. Japan |
| NEC PC-Engine HuCARD | Soukoban World Model MR90001 | 1990 | Media Rings Corp. Japan |
| NEC PC-Engine HuCARD | Space Harrier Model H67G-1002 P | 1988 | NEC Avenue, Ltd. Japan |
| NEC PC-Engine HuCARD | Space Invaders - Fukkatsu no Hi Model TP02008 | 1990 | Taito Corp. Japan |
| NEC PC-Engine HuCARD | Spin Pair Model MR90002 | 1990 | Media Rings Corp. Japan |
| NEC PC-Engine HuCARD | Spiral Wave | 1991 | Media Rings Corp. Japan |
| NEC PC-Engine HuCARD | Splatterhouse Model NC90002 P | 1990 | NAMCOT Japan |
| NEC PC-Engine HuCARD |  Splendid Saga | 1990 | Masaya |
| NEC PC-Engine HuCARD | Stratego Model JC63012 P | 1992 | Victor Musical Industries, Inc. Japan |
| NEC PC-Engine HuCARD | Street Fighter II' - Champion Edition Model HE93002 P | 1993 | NEC Home Electronics, Ltd. |
| NEC PC-Engine HuCARD | Strip Fighter II | 1993 | Games Express |
| NEC PC-Engine HuCARD | Super Metal Crusher | 1991 | Pack-In-Video Co., Ltd. Japan |
| NEC PC-Engine HuCARD | Super Momotarou Dentetsu | 1989 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Super Momotarou Dentetsu II | 1991 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Super Star Soldier Model HE-1097 | 1990 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Super Volleyball Model VS-90002 | 1990 | Video System Co., Ltd. Kyoto, Japan |
| NEC PC-Engine HuCARD | Susanoo Densetsu | 1989 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Taito Chase H.Q. Model TP02006 P | 1990 | Taito Corp. Japan |
| NEC PC-Engine HuCARD | Takahashi Meijin no Shin Bouken Jima Model HC92055 | 1992 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Takeda Shingen | 1989 | Aicom Corp. Japan |
| NEC PC-Engine HuCARD | Tatsu no Ko Fighter Model TON89001 | 1989 | Tonkin House Japan |
| NEC PC-Engine HuCARD | Tatsujin Model TP-04022 | 1992 | Taito Corp. Japan |
| NEC PC-Engine HuCARD | Tennokoe Bank | 1991 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Tenseiryuu - Saint Dragon Model AC90001 P | 1990 | Aicom Corp. Japan |
| NEC PC-Engine HuCARD | Terra Cresta II - Mandoraa no Gyakushuu Model NB92006 | 1992 | Nichibutsu Nihon Bussan Co., Ltd. Osaka, Japan |
| NEC PC-Engine HuCARD | The Kung Fu Model HC62001 | 1987 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | The New Zealand Story Model TP02007 P | 1990 | Taito Corp. Japan |
| NEC PC-Engine HuCARD | The Ninja Warriors Model TP01002 | 1989 | Taito Corp. Japan |
| NEC PC-Engine HuCARD | The Tower of Druaga Model NC92003 P | 1992 | NAMCOT Japan |
| NEC PC-Engine HuCARD | Thunder Blade Model NAPH-1015 P | 1990 | NEC Avenue, Ltd. Japan |
| NEC PC-Engine HuCARD | Time Cruise II Model FA03-010 | 1991 | Face Co., Ltd. Tokyo, Japan |
| NEC PC-Engine HuCARD | Titan | 1991 | Naxat Soft. Japan |
| NEC PC-Engine HuCARD | Toilet Kids Model MR92005 | 1992 | Media Rings Corp. Japan |
| NEC PC-Engine HuCARD | Tora-he no Michi Model JC63004 | 1990 | Victor Musical Industries, Inc. Japan |
| NEC PC-Engine HuCARD | Toshi Tensou Keikaku - Eternal City Model NX91003 | 1991 | Naxat Soft. Japan |
| NEC PC-Engine HuCARD | Toy Shop Boys Model JC63009 | 1990 | Victor Musical Industries, Inc. Japan |
| NEC PC-Engine HuCARD | Tricky Model AI-03004 | 1991 | IGS Corp. Information Global Service |
| NEC PC-Engine HuCARD | Tsuppari Oozumou - Heisei Ban | 1993 | Naxat Soft. Japan |
| NEC PC-Engine HuCARD | Tsuru Teruhito no Jissen Kabushiki Bai Bai Game | 1989 | Intec, Inc. Japan |
| NEC PC-Engine HuCARD |  TV Sports Basketball Model JC63014 | 1993 | Victor Musical Industries, Inc. Japan |
