| Sony PSP UMD |  SBK 09 - Superbike World Championship | 2009 | Black Bean Games |
| Sony PSP UMD | Secret Agent Clank | 2008 | Sony Computer Ent. America SCEA CA, USA |
| Sony PSP UMD | Sega Genesis Collection Model ULUS-10192 | 2006 | SEGA of America, Inc. San Francisco, CA, USA |
| Sony PSP UMD | Sega Mega Drive Collection Model ULES-00556 | 2007 | SEGA Corp. |
| Sony PSP UMD | Sega Rally | 2007 | SEGA Europe Ltd. |
| Sony PSP UMD | Sega Rally Revo Model ULUS-10311 | 2007 | SEGA of America, Inc. San Francisco, CA, USA |
| Sony PSP UMD | Sengoku Basara - Battle Heroes | 2009 | Capcom Co., Ltd. Japan |
| Sony PSP UMD | Sengoku Basara - Chronicle Heroes Model ULJM-05903 | 2011 | Capcom Co., Ltd. Japan |
| Sony PSP UMD | Shin Megami Tensei - Akuma Zensho | 2005 | Atlus Co., Ltd. Japan |
| Sony PSP UMD | Shin Megami Tensei - Persona 2 Innocent Sin Model ULUS-10584 | 2011 | Atlus Co., Ltd. Japan |
| Sony PSP UMD |  Shin Megami Tensei: P3P - Persona 3 Portable Model ULES-01523 | 2011 | Ghostlight, Ltd. |
| Sony PSP UMD | Shin Megami Tensei: P3P - Persona 3 Portable Model ULUS-10512 | 2010 | Atlus USA, Inc. CA, USA |
| Sony PSP UMD | Shin Sangoku Muso - MultiRaid | 2009 | KOEI Co., Ltd. Japan |
| Sony PSP UMD | Shin Sangoku Musou | 2004 | KOEI Co., Ltd. Japan |
| Sony PSP UMD | Shin Sangoku Musou - 2nd Evolution | 2006 | KOEI Co., Ltd. Japan |
| Sony PSP UMD | Shiokaze no Kieru Umi ni | 2011 | Palace Japan |
| Sony PSP UMD | Shirokuma Bell Stars - Happy Holidays! Model ULJM-06111 | 2012 | Boost On Japan |
| Sony PSP UMD | Shrek Smash N' Crash Racing Model ULUS-10194 | 2006 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Sony PSP UMD | Shrek the Third | 2007 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Sony PSP UMD | Sid Meier's Pirates! Model ULUS-10224 | 2007 | 2K Games, Inc. New York, NY, USA |
| Sony PSP UMD | Silent Hill - Shattered Memories Model ULUS-10450 | 2010 | Konami Digital Ent. Co., Ltd. |
| Sony PSP UMD | Silent Hill 0rigins Model ULUS-10285 | 2007 | Konami Digital Ent. Co., Ltd. |
| Sony PSP UMD | Silverfall Model ULES-00808 | 2007 | 2K Games, Inc. New York, NY, USA |
| Sony PSP UMD | Smart Bomb Model ULUS-10016 | 2005 | Eidos Interactive |
| Sony PSP UMD | Smash Court Tennis 3 | 2007 | NAMCO Bandai Games, Inc. Japan |
| Sony PSP UMD | SNK Arcade Classics Vol.1 Model ULES-01105 | 2008 | Ignition Ent., Ltd. |
| Sony PSP UMD | SNK Arcade Classics Vol.1 Model ULJS-00297 | 2010 | SNK Playmore Japan |
| Sony PSP UMD | SNK Arcade Classics Vol.1 Model ULJS-193 | 2009 | SNK Playmore Japan |
| Sony PSP UMD | SNK Arcade Classics Vol.1 Model ULUS-10338 | 2008 | SNK Playmore Japan |
| Sony PSP UMD |  SNK Best Collection: Metal Slug Complete Model ULJS-00206 | 2009 | SNK Playmore Japan |
| Sony PSP UMD | Snoopy vs. the Red Baron | 2006 | NAMCO Bandai Games, Inc. Japan |
| Sony PSP UMD | SOCOM U.S. Navy SEALs - Fireteam Bravo 2 | 2006 | Sony Computer Ent. America SCEA CA, USA |
| Sony PSP UMD | SOCOM U.S. Navy SEALs - Fireteam Bravo Model UCUS-98615 | 2005 | Sony Computer Ent. America SCEA CA, USA |
| Sony PSP UMD | Sonic Rivals | 2006 | SEGA of America, Inc. San Francisco, CA, USA |
| Sony PSP UMD | Sorairo Portable Model ULJM-06138 | 2012 | CyberFront Corp. Japan |
| Sony PSP UMD | Sound Novel Portable Machi - Unmei no Kousaten - Tokubetsu-hen Model ULJM-05111 | 2006 | SEGA Corp. |
| Sony PSP UMD | Spac3 Invaders Extr3me | 2008 | Square Enix Co., Ltd. Japan |
| Sony PSP UMD | Space Invaders Evolution | 2006 | Rising Star Games, Ltd. UK |
| Sony PSP UMD | Space Invaders Pocket Model ULJM-05015 | 2005 | Taito Corp. Japan |
| Sony PSP UMD | Spectral Souls - Resurrection of the Ethereal Empire Model ULUS-10076 | 2006 | NIS America, Inc. USA |
