| Panasonic 3DO CD |  Seal of the Pharaoh Model FZ-SM1751 | 1994 | Panasonic Japan |
| Panasonic 3DO CD | Sesame Street - Numbers | 1994 | EA*Kids |
| Panasonic 3DO CD | Sewer Shark | 1994 | Digital Pictures |
| Panasonic 3DO CD | Sex | 1994 | Vivid Interactive |
| Panasonic 3DO CD | Shadow Warriors | 1994 | T&E Soft. Japan |
| Panasonic 3DO CD | Shanghai - Banri no Choujou | 1994 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Panasonic 3DO CD | Shanghai - Triple-Threat | 1994 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Panasonic 3DO CD | Shelley Duvall's It's A Bird's Life | 1992 | Sanctuary Woods |
| Panasonic 3DO CD |  Shock Wave - Operation JumpGate demo | 1995 | Electronic Arts CA, USA 14633 |
| Panasonic 3DO CD | Shock Wave demo | 1994 | Electronic Arts CA, USA 14633 |
| Panasonic 3DO CD | Shock Wave Model 722207 | 1994 | Electronic Arts CA, USA 14633 |
| Panasonic 3DO CD |  Shock Wave Model FZ-SJ1657 | 1994 | Electronic Arts Victor, Inc. Japan |
| Panasonic 3DO CD | Shockwave 2 - Beyond the Gate | 1995 | Electronic Arts CA, USA 14633 |
| Panasonic 3DO CD | Shooter 2D Hb | 2008 | Games That Weren't |
| Panasonic 3DO CD | Sid Meier's C.P.U. Bach | 1994 | MicroProse, Ltd. Bristol, UK 015352 |
| Panasonic 3DO CD | Slam 'N Jam '95 | 1995 | BMG Interactive Ent. Japan |
| Panasonic 3DO CD | Slam-n-Jam '95 | 1995 | Crystal Dynamics |
| Panasonic 3DO CD | Slayer | 1994 | Mindscape, Inc. Northbrook, IL, USA 24294 |
| Panasonic 3DO CD | Snow Job Starring Tracy Scoggins | 1995 | 3DO Co., The CA, USA |
| Panasonic 3DO CD | Snowjob | 1995 | 3DO Co., The CA, USA |
| Panasonic 3DO CD | Soccer Kid | 1994 | 3DO Co., The CA, USA |
| Panasonic 3DO CD | Sotsugyou Graduation Final demo | 1994 | Shar Rock |
| Panasonic 3DO CD | Space Ace Model DH 65008 | 1995 | ReadySoft, Inc. Canada |
| Panasonic 3DO CD | Space Hulk - Vengeance of the Blood Angels | 1995 | Electronic Arts CA, USA 14633 |
| Panasonic 3DO CD | Space Pirates | 1994 | American Laser Games, Inc. Albuquerque, NM, USA |
| Panasonic 3DO CD | Space Shuttle | 1993 | Software Toolworks, The |
| Panasonic 3DO CD | Star Control II | 1994 | Crystal Dynamics |
| Panasonic 3DO CD | Star Control II | 1994 | BMG Interactive Ent. Japan |
| Panasonic 3DO CD | Star Fighter | 1995 | 3DO Co., The CA, USA |
| Panasonic 3DO CD | Star Wars - Rebel Assault Model 636201 | 1993 | Electronic Arts CA, USA 14633 |
| Panasonic 3DO CD | Star Wars - Rebel Assault Model FZ-SJ1663 | 1993 | Electronic Arts Victor, Inc. Japan |
| Panasonic 3DO CD | StarBlade demo | 1994 | Panasonic Japan |
| Panasonic 3DO CD | Starblade Model FZ-SJ5351 P | 1994 | NAMCO, Ltd. Japan |
| Panasonic 3DO CD | StarBlade Model FZ-SM5351 | 1994 | Panasonic Japan |
| Panasonic 3DO CD | Stellar 7 - Draxon no Gyakushuu | 1994 | Dynamix Part of the Sierra Family USA 20626 |
| Panasonic 3DO CD | Stellar 7 - Draxon's Revenge | 1993 | Dynamix Part of the Sierra Family USA 20626 |
| Panasonic 3DO CD | Strahl Model FZ-SM4651 | 1995 | Panasonic Japan |
| Panasonic 3DO CD | Striker - World Cup Special Model FZ-SK0001 | 1995 | Panasonic Japan |
| Panasonic 3DO CD | Super Real Mahjong P.V Model S-3D951 | 1995 | Seta Co., Ltd. Japan |
| Panasonic 3DO CD | Super Real Mahjong PIV + Aishou Shindan Model FZ-SJ6451 | 1995 | Seta Co., Ltd. Japan |
