| Sega CD |  Mary Shelley's Frankenstein | 1994 | Sony Imagesoft |
| Sega CD | MegaRace Model T-87025 | 1993 | Software Toolworks, The |
| Sega CD | Mickey Mania - Timeless Adventures of Mickey Mouse Model T-93265 | 1994 | Sony Imagesoft |
| Sega CD | Microcosm Model T-113015 | 1993 | Psygnosis, Ltd. |
| Sega CD | Midnight Raiders Model 4439 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega CD | Mighty Mighty Missile | 2004 | SEGA Corp. |
| Sega CD | Mighty Morphin Power Rangers Model 4442 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega CD | Mortal Kombat Model T-81025 | 1993 | Arena Ent. |
| Sega CD | NBA Jam Model T-81035 | 1994 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Sega CD | NFL Football Trivia Challenge Model T-135015 | 1994 | CapDisc |
| Sega CD | NFL's Greatest - San Francisco VS Dallas 1978-1993 Model 4202 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega CD | NHL '94 Model T-50015 | 1993 | EA Sports |
| Sega CD | Night Trap Model 4903 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega CD | Night Trap Model T-16202F | 1994 | Digital Pictures |
| Sega CD |  Night Trap Model T-162105 | 1995 | Digital Pictures |
| Sega CD | Note! Color Mechanica | 2014 | Good Deal Games |
| Sega CD | Novastorm Model T-113065 | 1994 | Psygnosis, Ltd. |
| Sega CD | Panic! Model T-13015 | 1994 | Data East Corp. Japan |
| Sega CD | Penn and Tellers Smoke and Mirrors | 199? | Absolute Ent., Inc. Midland Park, NJ, USA |
| Sega CD | Pitfall - The Mayan Adventure Model T-130025 | 1994 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Sega CD | Popful Mail Model T-127035 | 1995 | Working Designs |
| Sega CD | Power Factory featuring C+C Music Factory Model T-93035 | 1993 | Sony Imagesoft |
| Sega CD | PowerMonger Model T-50035 | 1994 | Electronic Arts CA, USA 14633 |
| Sega CD | Prince of Persia Model 4652 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega CD | Prize Fighter Model 4606 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega CD | Puggsy Model 113035 | 1993 | Psygnosis, Ltd. |
| Sega CD | Racing Aces Model 4607 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega CD | Radical Rex Model T-130035 | 1994 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Sega CD | RDF - Global Conflict Model T-86025 | 1994 | Absolute Ent., Inc. Midland Park, NJ, USA |
| Sega CD | Revenge of the Ninja Model T-49035 | 1993 | Renovation Products USA |
| Sega CD | Revengers of Vengeance Model T-22035 | 1994 | Extreme Ent. Group |
| Sega CD | Rise of the Dragon Model T-110035 | 1994 | Dynamix Part of the Sierra Family USA 20626 |
| Sega CD | Road Avenger Model T-6207 | 1993 | Renovation Products USA |
| Sega CD | Road Rash Model T-50085 | 1995 | Electronic Arts CA, USA 14633 |
| Sega CD |  Robo Aleste Model T-48015 | 1993 | Tengen, Inc. Milpilas, CA, USA |
| Sega CD | Rock Paintings + Hot Hits | 1992 | SEGA of America, Inc. San Francisco, CA, USA |
| Sega CD | Samurai Shodown Model T-60175 | 1995 | JVC Musical Industries, Inc. |
| Sega CD | Secret of Monkey Island Model T-60035 | 1993 | JVC Musical Industries, Inc. |
| Sega CD | Sega Classics Arcade Collection Model 4127 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega CD | Sega Classics Arcade Collection Model T-4127 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
