| IBM PC 5.25in. disk |  M.U.L.E. | 1985 | IBM Corp. International Business Machines |
| IBM PC 5.25in. disk | MACH 3 | 1987 | Loriciels France |
| IBM PC 5.25in. disk | Magic Pockets | 1992 | Mindscape, Inc. Northbrook, IL, USA 24294 |
| IBM PC 5.25in. disk | Make Your Own Murder Party Model 1185 | 1986 | Electronic Arts CA, USA 14633 |
| IBM PC 5.25in. disk | Manhunter - New York | 1988 | Sierra On-Line, Inc. USA 20626 |
| IBM PC 5.25in. disk | Marble Madness Model 1299 P | 1986 | Electronic Arts CA, USA 14633 |
| IBM PC 5.25in. disk | Martian Memorandum | 1991 | Access Soft., Inc. |
| IBM PC 5.25in. disk | Marvin the Moose | 1991 | Milliken Publishing |
| IBM PC 5.25in. disk | Master Ninja - Shadow Warrior of Death | 1986 | Paragon Soft. |
| IBM PC 5.25in. disk | Math Blaster | 1983 | Davidson & Associates, Inc. |
| IBM PC 5.25in. disk | Math Rabbit | 1986 | Learning Co., The |
| IBM PC 5.25in. disk | Maupiti Island | 1991 | Lankhor |
| IBM PC 5.25in. disk | Maze Adventures | 1986 | Keypunch Soft. |
| IBM PC 5.25in. disk | Mean 18 | 1987 | Accolade, Inc. San Jose, CA, USA 15605 |
| IBM PC 5.25in. disk | Mean Streets | 1989 | Access Soft., Inc. |
| IBM PC 5.25in. disk | Mech Brigade P | 1987 | SSI Strategic Simulations, Inc. 16685 |
| IBM PC 5.25in. disk | Medieval Lords - Soldier Kings of Europe Model 04138 | 1991 | SSI Strategic Simulations, Inc. 16685 |
| IBM PC 5.25in. disk | Mega Man | 1990 | Capcom USA, Inc. Santa Clara, CA, USA 13388 |
| IBM PC 5.25in. disk | Mega Man III | 1992 | Hi-Tech Expressions, Inc. |
| IBM PC 5.25in. disk | Megatraveller - The Zhodani Conspiracy | 1990 | Paragon Soft. |
| IBM PC 5.25in. disk | Menace P | 1989 | Psyclapse |
| IBM PC 5.25in. disk | Metal Gear | 1990 | Ultra Games Ultra Soft. Corp. |
| IBM PC 5.25in. disk | Metropolis | 1987 | Mastertronic, Ltd. UK 012967 |
| IBM PC 5.25in. disk | Miami Vice | 1989 | Capstone |
| IBM PC 5.25in. disk | Michael Crichton: Amazon Model AMZ-IB-D1 | 1984 | Telarium Corp. |
| IBM PC 5.25in. disk | Mickey's Space Adventure | 1985 | Sierra On-Line, Inc. USA 20626 |
| IBM PC 5.25in. disk | Microsoft Adventure | 1981 | IBM Corp. International Business Machines |
| IBM PC 5.25in. disk | Microsoft Decathlon | 1982 | Microsoft |
| IBM PC 5.25in. disk | Microsoft Flight Simulator Ver. 1.x | 1982 | Microsoft |
| IBM PC 5.25in. disk | Microsoft Flight Simulator Ver. 2.x | 1984 | Microsoft |
| IBM PC 5.25in. disk | Midway Campaign Model 40154 | 1983 | Microcomputer Games |
| IBM PC 5.25in. disk |  Midwinter | 1990 | MicroPlay Soft. |
| IBM PC 5.25in. disk | Midwinter Model 117148 | 1990 | Rainbird Soft. UK 012439 |
| IBM PC 5.25in. disk | Might and Magic - Book One: Secret of the Inner Sanctum | 1987 | New World Computing, Inc. |
| IBM PC 5.25in. disk | Mind Boggle | 1986 | Keypunch Soft. |
| IBM PC 5.25in. disk | Mindshadow Model DD-110 | 1984 | Activision, Inc. Mountain View, CA, USA 47875 |
| IBM PC 5.25in. disk | Mini-Putt Model 67111 | 1988 | Accolade, Inc. San Jose, CA, USA 15605 |
| IBM PC 5.25in. disk | Mini-Putt Model A70251EI | 1988 | Electronic Arts Home Computer Soft. UK 15839 |
| IBM PC 5.25in. disk | Modem Wars Model 1631 | 1988 | Electronic Arts CA, USA 14633 |
| IBM PC 5.25in. disk | Montezuma's Revenge | 1984 | BCI Soft. |
