| IBM PC 5.25in. disk |  Continuum Model 406-0429 | 1990 | Data East USA, Inc. |
| IBM PC 5.25in. disk | Cosmic Crusader | 1982 | Funtastic |
| IBM PC 5.25in. disk | Crazy Cars II | 1989 | Titus Gagny, France |
| IBM PC 5.25in. disk | Crime and Punishment | 1984 | Mindscape, Inc. Northbrook, IL, USA 24294 |
| IBM PC 5.25in. disk | Crime Wave | 1990 | Access Soft., Inc. |
| IBM PC 5.25in. disk | Crossfire | 1984 | Sierra On-Line, Inc. USA 20626 |
| IBM PC 5.25in. disk | Crossword Magic Model 85331 | 1985 | Mindscape, Inc. Northbrook, IL, USA 24294 |
| IBM PC 5.25in. disk | Crusade in Europe | 1985 | MicroProse, Ltd. Bristol, UK 015352 |
| IBM PC 5.25in. disk | Crush, Crumble and Chomp! Model 435D | 1983 | Epyx, Inc. Redwood City, CA, USA |
| IBM PC 5.25in. disk | Crypto Cube | 1983 | DesignWare |
| IBM PC 5.25in. disk | Crystal Caves - Episode 1-3 | 1991 | Apogee Soft. |
| IBM PC 5.25in. disk | Cutthroats Model IA3-IB1 | 1984 | Infocom, Inc. MA, USA 51051 |
| IBM PC 5.25in. disk | Cutthroats Model IA3-IB2 | 198? | Infocom, Inc. MA, USA 51051 |
| IBM PC 5.25in. disk | Cyborg | 1982 | Softsmith Soft. |
| IBM PC 5.25in. disk | Czorian Siege | 1983 | Sams Soft. |
| IBM PC 5.25in. disk | D/Generation | 1991 | Mindscape, Inc. Northbrook, IL, USA 24294 |
| IBM PC 5.25in. disk | Dakar 4x4 | 1987 | Coktel Vision |
| IBM PC 5.25in. disk | Dark Century Model 072079 | 1990 | Titus Gagny, France |
| IBM PC 5.25in. disk | David Wolf: Secret Agent | 1989 | Dynamix Part of the Sierra Family USA 20626 |
| IBM PC 5.25in. disk | Deadline Model IM1-IB1 | 1982 | Infocom, Inc. MA, USA 51051 |
| IBM PC 5.25in. disk | Defender of the Crown | 1987 | Mindscape, Inc. Northbrook, IL, USA 24294 |
| IBM PC 5.25in. disk | Defender of the Crown Model 85318 | 1987 | Cinemaware Corp. |
| IBM PC 5.25in. disk | Defender Model DX5504 | 1983 | Atarisoft Atari, Inc. |
| IBM PC 5.25in. disk | Deja Vu - A Nightmare Comes True Model 110006 | 1987 | Mindscape, Inc. Northbrook, IL, USA 24294 |
| IBM PC 5.25in. disk | Demon Stalkers - The Raid on Doomfane Model 1587 | 1989 | Electronic Arts CA, USA 14633 |
| IBM PC 5.25in. disk | Demon's Forge | 1987 | Mastertronic, Ltd. UK 012967 |
| IBM PC 5.25in. disk | Demon's Tomb - The Awakening | 1989 | Virgin Mastertronic International, Inc. USA |
| IBM PC 5.25in. disk | Demon's Winter | 1988 | SSI Strategic Simulations, Inc. 16685 |
| IBM PC 5.25in. disk | Desdemona | 1983 | Zephyr Services Pittsburgh, PA, USA |
| IBM PC 5.25in. disk | Destroyer | 1986 | Epyx, Inc. Redwood City, CA, USA |
| IBM PC 5.25in. disk | Dick Tracy | 1990 | Titus Gagny, France |
| IBM PC 5.25in. disk | Dick Tracy - The Crime-Solving Adventure | 1991 | Disney Soft. |
| IBM PC 5.25in. disk | Die Hard | 1989 | Activision, Inc. Menlo Park, CA, USA 47875 |
| IBM PC 5.25in. disk |  Dig Dug P | 198? | Thunder Mountain Northbrook, IL, USA |
| IBM PC 5.25in. disk | Dig Dug Model 14354 P | 1984 | Datasoft, Inc. Chatsworth, CA, USA |
| IBM PC 5.25in. disk | Dig Dug Model DX5506 P | 1983 | Atarisoft Atari, Inc. |
| IBM PC 5.25in. disk | Digger | 1983 | Windwill Soft. |
| IBM PC 5.25in. disk | Disney's DuckTales - The Quest for Gold | 1990 | Disney Soft. |
| IBM PC 5.25in. disk | Dnieper River Line Model 41754 | 1983 | Microcomputer Games |
| IBM PC 5.25in. disk | Donald Duck's Playground P | 1985 | Sierra On-Line, Inc. USA 20626 |
